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KMID : 0361120100240020114
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Korean Journal of Transplantation
2010 Volume.24 No. 2 p.114 ~ p.117
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Two Cases of Pneumocystis Pneumonia after Liver Transplantation Presenting with Different Clinical Manifestations
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Kim Youn-Jeong
Kim Sang-Il
Hong Kyoung-Wook
Chang Mine-Ok
Kim Ji-Il
You Young-Kyoung
Moon In-Sung
Kim Dong-Goo
Lee Myung-Duk
Kang Moon-Won
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Abstract
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Pneumocystis carinii pneumonia (PCP), now known as Pneumocystis jirovecii , is a fungal pathogen that causes opportunistic disease, especially pneumonia, in immunocompromised patients. The patients can have a spectrum of illnesses ranging from asymptomatic to fulminant respiratory failure. Here we report two cases with pneumocystis pneumonia after liver transplantation who presented with different clinical features. One patient developed acute respiratory failure requiring mechanical ventilation and expired due to PCP and a superimposed bacterial infection. The other patient was asymptomatic and discovered by regular X-ray check-up. He was successfully treated with trimethoprim/sulfamethoxazole. As shown by our cases, PCP presents with broad clinical manifestations and leads to various clinical courses in liver transplant recipients. Thus, Pneumocystis jirovecii has to be considered a potential pathogen of pneumonia in liver transplant recipients regardless of severity, especially one who is not on prophylactic medications. We consider prophylaxis of PCP in liver transplant recipients in our center.
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KEYWORD
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Pneumonia, Pneumocystis, Pneumocystis jirovecii, Liver transplantation
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